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pentobarbital will lessen the extent or impact of capivasertib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Potent or average CYP3A inducers reduce capivasertib exposure, which may lessen efficacy.pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by impacting he